MELINE is a professional depigmentation system exclusively developed for the management of hyperpigmentation. Based on clinical assessment and personalized treatment protocols, combines in-clinic treatments with prescribed homecare to deliver safe, effective, and long-term results..

Levels of Hyperpigmentation MELINE
classifies pigmentation based on depth

Epidermal Hyperpigmentation

• Superficial pigment location
• Faster response to treatment
• Commonly associated with sun exposure

Dermal Hyperpigmentation

• Deeper pigment deposition
• Requires combined and repeated treatments
• More resistant to therapy 

Mixed Hyperpigmentation

• Combination of epidermal and dermal components
• Requires individualized protocols
• Common in melasma cases 

Area-Specific Treatment Approach
MELINE provides targeted solutions for different anatomical areas:

• Face
• Eye area (e.g. dark circles)
• Body (e.g. axilla, inner thighs, back)

Treatment choice is based on:

• Pigmentation type
• Skin phototype
• Patient history

Active Ingredients & Mechanism of Action MELINE formulations combine active ingredients that act on multiple pathways:

Tyrosinase inhibitors → reduce melanin production

Melanogenesis regulators → control melanocyte activity

Exfoliating agents → promote epidermal renewal

Antioxidants & anti-inflammatory agents → reduce irritation and protect the skin This multi-target approach allows controlled and progressive improvement.

In-Clinic Treatments Professional applications
with high concentration of active ingredients, tailored to pigmentation depth and type.

Homecare Products Adjunctive therapy for:

• Maintenance of results
• Prevention of recurrence
• Continuous melanogenesis control 

MELINE Caucasian Skin Protocol 
Designed for hyperpigmentation in skin phototypes I–III. Targets melanogenesis regulation and gradual skin tone correction with controlled exfoliation.  

MELINE Intimate Treatment
For body and intimate area hyperpigmentation. Designed to improve skin tone in sensitive areas such as axilla and inner thighs.   

Mesoline (Mesotherapy)MELINE Dark Circles
Specialized treatment for periorbital hyperpigmentation. Improves skin tone and reduces the intensity of dark discoloration.  

MELINE Dark Spots
Targeted solution for localized pigmentation. Suitable for sun spots, post-inflammatory hyperpigmentation, and localisedlesions.